Tech & Science The world's smallest Mona Lisa is made from DNA

16:39  07 december  2017
16:39  07 december  2017 Source:   Engadget

Why ‘The Room’ Is the Best Worst Movie Ever

  Why ‘The Room’ Is the Best Worst Movie Ever James Franco’s ‘The Disaster Artist’ chronicles the making of Tommy Wiseau’s ‘The Room,’ a bizarre passion project considered by many to be the worst movie ever made.It’s something of a grand cosmic joke that Franco is receiving Oscar attention for his imitation of what may be the lousiest performance in big-screen history—namely, writer/director/star Tommy Wiseau’s turn as Johnny, a man whose relationship to fiancée Lisa (Juliette Danielle) is torn apart by her affair with his best friend Mark (Greg Sestero).

Leonardo da Vinci' s Mona Lisa painting isn't actually that big (30 inches tall), but Caltech researchers have found a way to make that seem downright gargantuan. They've used DNA to construct the smallest known Mona Lisa .

The Gun That Made the Twenties Roar. Animal Oddity Research Review. Boris Karloff in Frankenstein. Zombies in the Real World . Email This Post to a Friend. " The World ' s Smallest Mona Lisa ". Separate multiple emails with a comma. Limit 5.

  The world's smallest Mona Lisa is made from DNA © Provided by Engadget Leonardo da Vinci's Mona Lisa painting isn't actually that big (30 inches tall), but Caltech researchers have found a way to make that seem downright gargantuan. They've used DNA to construct the smallest known Mona Lisa. At several hundred nanometers across, they're roughly as large as a lone E. coli bacterium -- the iconic smile is just 100nm wide. The trick was an adaptation of a DNA "origami" method that got the gene strands to fold and assemble into the right shape.

The Mona Lisa is divided into squares, each of which is folded by using one long DNA strand manipulated by "staples" (short, custom-designed strands) that bind to and pull on it. After that, it's a matter of attaching the squares to a DNA canvas. You do that by isolating each square into a test tube and combining them in progressively larger squares (2x2, 4x4 and finally 8x8) until Mona Lisa shows her mysterious face. Each square has edges designed only to join in a specific way, so the wrong pieces can't attach to each other by mistake.

The Disaster Artist

  The Disaster Artist Since its small cinema release in Los Angeles in 2003, The Room has become a cult classic. Travel anywhere in the world and you’re bound to find a cinema showing it, with director, writer, producer and actor Tommy Wiseau’s unusual face plastered on posters. But how did this extraordinarily bad movie come to fruition? And what’s the story behind the mysterious Wiseau? That’s what actor Greg Sestero hoped to capture in his book The Disaster Artist, about the making of The Room and his involvement in the project playing the character Mark alongside Jonny (Wiseau), the banker who will do “anything for his princess” Lisa. As much as we’d love to go back in time and behind the scenes ourselves, James Franco has done that for us with his big screen adaptation of The Disaster Artist, in which he transforms himself into Wiseau, while his younger brother Dave portrays Sestero. Audiences get to witness the moment Greg was first bowled over by Tommy’s unusual acting skills, involving him throwing a chair around a stage and thrusting himself off the floor during a class. Teacher Jean (Melanie Griffith) isn’t impressed by Tommy’s so-called performance – in fact, no one is, except Greg, who nervously approaches him after and asks if they can do a scene together. And so begins the beginning of a friendship which sees them pack up and leave San Francisco for Los Angeles, despite the nerves of Greg’s mother (Megan Mullally), who immediately questions how old Tommy is.

Los Angeles: Scientists have created the world ' s smallest copy of Italian polymath Leonardo da Vinci's famous painting ' Mona Lisa ' using DNA . "To make our technique readily accessible to other researchers who are interested in exploring applications using micrometre-scale flat DNA

Los Angeles, Dec 7 (PTI) Scientists have created the world ’ s smallest copy of Italian polymath Leonardo da Vinci’s famous painting ‘ Mona Lisa ’ using DNA . These strict base-pairing “rules” make it possible to design DNA origami. A large DNA canvas is assembled out of many smaller square

As you can use a combination of software and automatic liquid handling to make these mini paintings, you're really just limited by your creativity -- the team also 'drew' portraits of bacteria and a rooster to show what was possible. And that, in turn, could lead to more practical uses. DNA-based nanostructures like this could help build extremely dense circuits, exotic organic materials or just tests for chemical and molecular interactions. This might not be the smallest piece of art you've ever seen, but the technology behind it could be incredibly useful beyond recreating masterpieces.

Caltech

Tiny Donkey May Take the Title of World's Smallest .
He will eligible for the honor once he turns 1-year-old.The miniature American donkey, Ottie, is six inches shorter than the current Guinness World Record holder, 10-year-old KneeHi, which stands at 25.29 inches.

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